Off-target effects of NGTs: CRISPR/Cas “fatigues chromatin”
Touted as precise, simple and inexpensive, CRISPR/Cas is the flagship tool underpinning the promises made by GMOs derived from new genetic modification techniques (NGTs). Already at the centre of several controversies, CRISPR/Cas is once again making headlines. This time, it concerns the discovery of a new type of harmful effect.