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Development of resistance

25 years later, insecticidal GMOs face insect resistance

43 detections of insects having acquired resistance to the Bt proteins supposed to kill them were listed in a scientific article in 2023. 43 cases out of 73 studied, i.e. more than half. For the authors of the article, the use of insecticidal GMOs has been crowned with success, as in several cases it has made it possible to reduce or even eradicate local pests. But failures also occurred due to resistance. The authors believe that the future lies in a combination of technologies, among which is RNA interference.

Environment

Development of resistance

In Spain, are some insects beginning to resist GM maize?

For almost 15 years, European and French experts have been recommending that Bayer improve environmental monitoring of commercial Mon810 corn crops in Spain and Portugal. This improvement is necessary, they say, to prevent target insects such as the European corn borer and sesamia from developing resistance to the insecticide produced by this transgenic corn. But year after year, Bayer only partially responds to these requests. Yet concerns are becoming increasingly serious and concrete, as demonstrated by the latest EFSA opinion, published in August 2024.

Polyploidy induction

Making salmon sterile… and able to reproduce

In Norway, the Institute of Marine Research (IMR)i has filed a trial application, in 2023, for genetically modified salmon (VIRGIN® salmon). These salmon, bred in cages in the open sea, would be sterile to prevent them from interbreeding with wild populations in the event of accidental dissemination. The Norwegian Environment Agency asked the Norwegian Scientific Committee for Food and the Environment (VKM) to assess the associated environmental risks. VKM’s opinion was highly critical, stating that there was insufficient evidence to consider the trial safeii. In April 2024, after having considered new data, VKM reiterated its negative opinion on this GM salmon trial.

Biopiracy

Interconnections between new biotechnologies and DSI or GSD

What are the links between new techniques of genetic modification, digitization of genetic sequences information and patents? Inf’OGM publishes here an analysis presented in June 2024 at a regional workshop organized by the African Center for Biodiversity, in Durban (South Africa). It was written by Guy Kastler, representative of the international farmers’ organization La Via Campesina at various ITPGRFA and CBD meetings. 

Mutagenesis

De Bolster: another Dutch SME under patent threat

In April 2024, Inf’OGM reported on its interview with a Dutch seed company feeling threatened by KWS patents. This is not an isolated case since De Bolster, another Dutch seed company, has had to apply constant legal vigilance for several years to prevent its varietal varieties from being covered by an ever-increasing number of patent rights, otherwise its survival would be jeopardized. Frans Carree, Director of De Bolster’s Variety Development Department, answered our questions.

Contamination

Illegal GMO plants and micro-organisms in Europe

Between 1 January 2021 and the present day, the European Union has had to deal with almost fifty cases of the illegal presence of GMOs on its territory. Most of the cases reported by the national authorities involve GMO plants originating in Asian countries such as Vietnam and Thailand, but also in other countries such as Ukraine, the United States and, more surprisingly, France… GMO micro-organisms have also been detected in batches of food additives used in human and animal nutrition.

Development of resistance

Catalonia: GMO Clearfield rapeseeds do not have better yields

In Spain, the public agronomy institute Irta regularly carries out evaluations of several varieties of rapeseed. Recently, they introduced into their evaluation some Clearfield rapeseed varieties, herbicide tolerant varieties modified via in vitro mutagenesis. Result: these GMOs, grown commercially in Europe outside the legal framework, do not have better yields than their conventional counterparts.

Innovation

Synthetic Biology, talks are involving GMOs

For the past fifteen years, governments have been discussing “synthetic biology” on an international level. If to date, an “operational” definition exists, the outlines of this field remain hard to draw. Are talks of “synthetic biology” simply a change of semantics, or a genuinely new frontier of the biotechnology field? For the moment, examples of organisms or molecules obtained by synthetic biology are accumulating: unnatural proteins, GMO plants, GMO bacteria, recreated viruses, modification of living organisms directly in the environment, GMO insects, xenobacteria…

Innovation

GMO viruses as laboratory tools to be spread in the environment ?

In a recent article, researchers detail several ongoing projects for the genetic modification of viruses. Some of these could be deliberately released into the environment. On February 7, 2024, the European Parliament asked the European Commission to study the potential deregulation of these GMO viruses. A general overview of those projects seems therefore necessary.

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